Best Electronic Data Capture (EDC) Software


Electronic data capture (EDC) software replaces the traditional and very manual process of managing clinical trial data with an electronic system. At its core, EDC software streamlines the collection, review, and processing of clinical trial data. Clinical trial management software is bolstered by EDC software; some even offer EDC functionality within the CTMS. Benefits of using EDC software include improved data quality and study efficiency, as well as an improved ability to meet regulatory compliance. Contract research organizations (CROs), clinical trial sponsors, and study sites all utilize EDC software.

To qualify for inclusion in the EDC category, a product must:

Capture and store clinical trial data
Simplify the process of sharing and exporting of data
Enforce querying of stored clinical trial data

Top 5 Electronic Data Capture (EDC) Software

  • REDCap
  • Oracle Clinical
  • Medrio EDC
  • Castor EDC
  • OpenClinica

Compare Electronic Data Capture (EDC) Software

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REDCap (Research Electronic Data Capture) is a secure web application for building and managing online surveys and databases.


Oracle Clinical

Oracle Remote Data Capture provides a single application and infrastructure for electronic data capture and clinical data management.


Medrio EDC

Medrio’s Electronic Data Capture (EDC) platform and complimenting eClinical solutions such as ePRO, eConsent and Direct Data Capture (DDC) have been trusted by major pharmaceutical, biotech, CRO, animal health, medical device, and diagnostic companies since 2005. We’re not only trusted, but we’re also more efficient with skip logic and edit checks built into the platform as standard, and a study build timeline that’s 75% faster than the industry average.


Castor EDC

Castor is a cloud-based Electronic Data Capture, eCRF, ePRO, eCOA, eConsent, and Decentralized Trials platform that enables researchers to easily capture and integrate data from any source in real-time. Highlights: ● Decentralize your trials with Castor eConsent, ePRO, and video. ● Build a study within hours using an intuitive form builder ● 90% of studies in Castor are built and pass UAT in less than 4 weeks ● Capture patient, clinician, EMR/EHR, and device data on a central platform ● Monitor study progress through real-time reporting ● Compliant with 21 CFR Part 11, GCP, GDPR and HIPAA ● ISO27001 and ISO9001 certified ● Top-rated EDC and ePRO systems ● World-class support 



The OpenClinica Enterprise Edition is an enhanced, fully-supported build that is ideal for mission-critical settings.


MATRIX EDC is a cloud-based clinical data management application. EDC supports electronic, paper-based or hybrid studies.

Medidata Rave

Medidata Rave is a cloud–based clinical data management system used to electronically capture, manage, and report clinical research data. It enables the user to record patient information (ie, visit, lab, and adverse event data) using forms that are customized for each study.



PatientIQ is a cloud-based software platform and patient engagement technology that automates the collection of patient-reported outcomes. It also offers procedure-specific education modules to help prepare patients for treatments and proactively monitor their recovery. The platform’s built-in analytics and biostatistical modeling engine generate actionable insights for quality improvement, research, and marketing purposes. The collected data can also be used to collaborate and benchmark with other institutions. The software comes with full-service support and is easily configurable around organization-specific workflows.

Research Manager

Research Manager supports researchers and organisations in preparing, executing and administering (clinical) research data. Our expertise is the collection, validation and enrichment of data. With Research Manager, we offer a research platform that allows researchers to have all functionalities and information in one place and to share it with each other. The platform facilitates researchers who want to be prepared for a future where the patient, access to data, and sharing data are key. A quick overview of our three different solutions: ●Solution 1, Data Management (EDC): Electronic Data Capture module which complies with Good Clinal Practice, in order to collect, validate and enrich data. ●Solution 2, Study Management: Automizes the fully administrative process regarding the request, approval, and execution of clinical studies. ●Solution 3, MERC Management: The MERC can fully digitalize the process surrounding the submitting and testing of studies. Use the link below to book a free demonstration: ➞ https://my-researchmanager.com/en/demorequest/ Use the link below to try our configurator for Data Management (EDC): ➞ https://form.jotformeu.com/210814287728360 Use the link below for more information about Study Management (CTMS) ➞ https://my-researchmanager.com/en/prijzen-study-management-en/ Use the link below for more information about MERC Management ➞ https://my-researchmanager.com/en/prijzen-metc-en/



TrialKit, a cloud-based platform available via a web interface and downloadable native mobile app, enables end-to-end clinical trial management for pharmaceutical, biotechnology, and medical device companies of all sizes. Design and deploy regulatory compliant studies in days instead of weeks using our intuitive forms designer that requires no programming. Over 10,000 global users have leveraged the flexibility of TrialKit to deploy over 1,100 studies across all phases of clinical development.

Clear Clinica

Clear Clinica is an Electronic Data Capture (EDC) software that allows to store clinical trial data on secure servers, get faster statistical reports and have risks apps monitoring data.


A Clinical Data Management System (CDMS), Clinical Trial Management System (CTMS) and Electronic Data Capture System (EDC) all in one powerful, integrated solution.

ClinPlus CTMS

ClinPlus CTMS was designed specifically to help sponsors and CROs overcome the technical challenges associated with managing clinical trials and was developed on the principle that by improving user accessibility and communications.


Clireo eTMF is supported by a complete cloud-based document management system to facilitate any eTMF business process. Clireo eTMF includes inspector portal, workflow, version control, document staging areas, FTP connectivity, and a full standards-based API. Easily add Clireo eCTD for global regulatory e-submissions.

CTMS by Datatrak

The DATATRAK ONE Unified Experience removes complexities, activating better site compliance, better data, and safer trials.

Dacima Clinical Suite

Dacima Clinical is an advance electronic data capture (EDC) and clinical data management system (CDMS) for capturing, managing and reporting clinical research data and optimizing data collection by efficiently streamlining clinical data collection process.

Forte EDC

Forte EDC supports leading academic research centers, cancer centers, and health systems in running successful and compliant IITs.

READ MORE: Best Electronic Data Capture (EDC) Software

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